PARCOURS

2003 : Doctorate from the University of Bordeaux (France)

2012 - present : Principal Scientist at INRAE
2007 - 2009 : Scientist then Assistant Professor at the JCVI Synthetic Biology
2004 - 2007 : Post-doctoral fellow at the JCVI Synthetic Biology team            

RESEARCH GATE : https://www.researchgate.net/profile/Carole_Lartigue
LINKEDIN : https://fr.linkedin.com/in/carole-lartigue-6740349

RESEARCH

My scientific path has started in a context where genetic tools were lacking for the functional genomics of mollicutes while genome sequences were getting available for several species. During my PhD studies in A. Blanchard lab’s, most of my work has been dedicated to the development of replicative plasmids and transformation methods that could take advantage of all the knowledge from the genome sequence to investigate cell physiology and host-pathogen interactions. Then, I joined Dr. J. Glass’ group as a post-doctoral fellow to work on the emerging so-called synthetic biology (SB) project developed at the J. Craig Venter Institute. There, I was one of the main actors who accomplished the complete chemical synthesis of a mycoplasma genome, its assembly into yeast and its transplantation into a phylogenetically related recipient cell. This work opened the way to many developments for the study and the manipulation of mollicutes and, hopefully in the future, many other micro-organisms. I’m now working as a principal scientist in A. Blanchard lab’s, and our team is at the front line of the major developments in synthetic biology field.

PUBLICATIONS

Full publications list on the HAL-INRAE portal

ORCID : https://orcid.org/0000-0001-5550-7579    

FURTHER INFORMATION

MAIN COLLABORATORS

• Matthieu Jules (Institut Micalis, UMR1319, INRA) Jouy-en-Josas, FRANCE   
• C. Bébéar (USC EA 3671) Bordeaux, FRANCE
• F. Thiaucourt and Lucia Manso-Sliva (CIRAD), Montpellier, FRANCE
• Sanjay vashee and John Glass (J. Craig Venter Institute) Rockville and San Diego, USA
• Joerg Jores and Fabien Labroussaa (Bern University), Switzerland
• Elise Schiek (International Livestock Research institute), Kenya
• Sébastien Rodrigues (Sherbrooke University) Québec, Canada
• Luis Serrano and Maria Lluch Senar (Centre for Genomic Regulation), Barcelona, Spain
• Joerg Stülke (Göttingen University), Göttingen, Germany
• Mark Isalan and Alicia Broto (Imperial College), United Kingdom
• Vitor Martins dos Santos (Wageningen University), Netherlands
• Markus Schmidt (PME “Biofaction”), Austria